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Principal Investigator: Zhejian Ji 季哲剑, Ph.D.
School of Life Sciences, Westlake University
ATP is an essential energy currency in our cells, just like electricity to our home. We use a wide variety of electrical appliances in our daily life. Similarly, our cells employ various ATPases, which utilize energy from ATP hydrolysis to remodel their substrate molecules. The AAA-family ATPases are powerful nano-scale molecular machines that can remodel macromolecules, such as proteins and DNA. Their functions range from protein translocation and degradation, to complex assembly and disassembly.
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