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Principal Investigator: Zhejian Ji 季哲剑, Ph.D.
Westlake Laboratory
School of Life Sciences, Westlake University

Protein Machines

ATP is an essential energy currency in our cells, just like electricity to our home. We use a wide variety of electrical appliances in our daily life. Similarly, our cells employ various ATPases, which utilize energy from ATP hydrolysis to remodel their substrate molecules. The AAA-family ATPases are powerful nano-scale molecular machines that can remodel macromolecules, such as proteins and DNA. Their functions range from protein translocation and degradation, to complex assembly and disassembly.
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