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Principal Investigator: Zhejian Ji 季哲剑, Ph.D.
Westlake Laboratory
School of Life Sciences, Westlake University
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Protein Machines
![Figure 1.png](https://static.wixstatic.com/media/1be0fc_3eac0e5d4c8b4cb493e14fb373e4fe76~mv2.png/v1/fill/w_600,h_318,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/Figure%201.png)
ATP is an essential energy currency in our cells, just like electricity to our home. We use a wide variety of electrical appliances in our daily life. Similarly, our cells employ various ATPases, which utilize energy from ATP hydrolysis to remodel their substrate molecules. The AAA-family ATPases are powerful nano-scale molecular machines that can remodel macromolecules, such as proteins and DNA. Their functions range from protein translocation and degradation, to complex assembly and disassembly.
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